The nurse states that bone marrow toxicity does not suppress ...

[ss2343]

The nurse states that bone marrow toxicity does not suppress which type of cells?
 
  1. White blood cells
  2. Platelets
  3. T cells
  4. Red blood cells

Question 2

The nurse tells the client that alkylating agents kill cancer cells by:
 
  1. containing substances from bacteria that can kill cancer cells.
  2. disrupting critical cellular pathways of cancer cells.
  3. changing the shape of the DNA double helix and preventing DNA from duplicating during cell division.
  4. blocking substances necessary for continued growth of tumors.

[momo1250]

Answer to Question 1

Correct Answer: 3
Rationale 1: Bone marrow toxicity does decrease white blood cells.
Rationale 2: Bone marrow toxicity does decrease platelets.
Rationale 3: Bone marrow toxicity does not specifically decrease T cells.
Rationale 4: Bone marrow toxicity does decrease red blood cells.
Global Rationale: Myelosuppression (bone marrow suppression) is the primary dose-limiting toxicity of many of these drugs. Within days after administration, the numbers of erythrocytes, leukocytes, and platelets begin to decline, reaching a nadir at 9 to 14 days. T-cells are not affected by bone marrow toxicity.

Answer to Question 2

Correct Answer: 3
Rationale 1: This is the action of antibiotic antineoplastics.
Rationale 2: This is the action of antimetabolites.
Rationale 3: This is the action of alkylating agents.
Rationale 4: This is the action of hormone antagonists.
Global Rationale: Alkylating agents kill cancer cells by altering the shape of the DNA double helix and preventing the DNA from duplicating during cell division. Antibiotic antineoplastics contain substances from bacteria that can kill cancer cells. Antimetabolites disrupt critical cellular pathways of cancer cells. Hormone antagonists block substances necessary for the continued growth of tumors.

[ss2343]

Both answers were spot on, thank you once again

[momo1250]

Great! Please up vote