This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A client is suffering from end-stage renal disease. Because of this condition, the nurse monitors ... (Read 37 times)

Mr.Thesaxman

  • Hero Member
  • *****
  • Posts: 514
on: Jul 23, 2018
A client is suffering from end-stage renal disease. Because of this condition, the nurse monitors drug levels to assess for which phenomenon?
 
  a. Toxicity
  b. Subtherapeutic levels
  c. Drug ineffectiveness
  d. Poor compliance

Question 2

A client asks why the oral dose of her pain medication is higher than the intravenous dose. The nurse explains that with the oral dose, only 20 to 40 of the drug may actually enter systemic circulation.
 
  This reduces the amount of active drug. What is the term for this effect?
  a. Protein binding
  b. Bioavailability
  c. Hepatic first pass
  d. Pinocytosis


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

thall411

  • Sr. Member
  • ****
  • Posts: 332
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: A
The primary route for drug elimination is the renal system. If kidney function is impaired, drugs may reach toxic levels.

Answer to Question 2

ANS: B
Bioavailability is the percentage of the administered drug dose that reaches the systemic circulation. Oral drugs that have a high first-pass hepatic metabolism may have a bioavailability of only 20 to 40 on entering systemic circulation. To obtain the desired drug effect, the oral dose could be three to five times larger than the drug dose for IV use.


Mr.Thesaxman

  • Member
  • Posts: 514
Reply 2 on: Jul 23, 2018
Great answer, keep it coming :)

patma1981

  • Member
  • Posts: 292
Reply 3 on: Yesterday
Gracias!

« previous next »
 

Did you know?

GI conditions that will keep you out of the U.S. armed services include ulcers, varices, fistulas, esophagitis, gastritis, congenital abnormalities, inflammatory bowel disease, enteritis, colitis, proctitis, duodenal diverticula, malabsorption syndromes, hepatitis, cirrhosis, cysts, abscesses, pancreatitis, polyps, certain hemorrhoids, splenomegaly, hernias, recent abdominal surgery, GI bypass or stomach stapling, and artificial GI openings.

Did you know?

Acetaminophen (Tylenol) in overdose can seriously damage the liver. It should never be taken by people who use alcohol heavily; it can result in severe liver damage and even a condition requiring a liver transplant.

Did you know?

According to the Migraine Research Foundation, migraines are the third most prevalent illness in the world. Women are most affected (18%), followed by children of both sexes (10%), and men (6%).

Did you know?

Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

Did you know?

Patients who cannot swallow may receive nutrition via a parenteral route—usually, a catheter is inserted through the chest into a large vein going into the heart.

Identify each stage of the life cycle Identify each stage of the life cycle
Nurse administering enteral nutrition through a feeding tube. Nurse administering enteral nutrition through a feeding tube.
Drugs to Treat Alzheimer’s Disease Drugs to Treat Alzheimer’s Disease
An OBD-II active test. The PCM opens the EGR valve and then monitors the MAP sensor and/or engine ... An OBD-II active test. The PCM opens the EGR valve and then monitors the MAP sensor and/or engine ...
The client is positioned for the examination The client is positioned for the examination
Client is positioned Client is positioned
Video: Definition of heart rate

For a complete list of videos, visit our video library