« previous next »

Author Question: Ketoconazole is used as an alternative to amphotericin B for less severe systemic mycosis. Which are ... (Read 24 times)

tingc95

  • Hero Member
  • *****
  • Posts: 556
on: Jul 23, 2018
Ketoconazole is used as an alternative to amphotericin B for less severe systemic mycosis. Which are the primary reasons for choosing ketoconazole? (Select all that apply.)
 
  a. It can be given orally.
  b. It can be used safely in patients with he-patic dysfunction.
  c. It can be given once weekly rather than daily.
  d. It is effective for severe, acute infections.
  e. It is less toxic.

Question 2

A nurse is caring for a patient who has a superficial fungal infection and notes that the provider has ordered 200 mg of ketoconazole Nizoral 200 mg PO once daily. Which action by the nurse is correct?
 
  a. Administer the drug as ordered.
  b. Contact the provider to discuss twice daily dosing.
  c. Discuss a 400-mg daily drug regimen with the provider.
  d. Request an order for a different antifungal medication.


gasdhashg

  • Sr. Member
  • ****
  • Posts: 335
Reply #1 on: Jul 23, 2018
Answer to Question 1

A, E
Ketoconazole is given instead of amphotericin B because it is less toxic and can be administered orally. Amphotericin B is administered intravenously. Ketoconazole is hepatotoxic; it is given daily. Ketoconazole is less useful for severe, acute infections.

Answer to Question 2

D
Because of the risk of serious and potentially fatal hepatic necrosis with oral ketoconazole, it is not recommended for use in treating superficial fungal infections. Another antifungal medication should be ordered.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question

tingc95

  • Hero Member
  • *****
  • Posts: 556
Reply #2 on: Jul 23, 2018
TY


gasdhashg

  • Sr. Member
  • ****
  • Posts: 335
Reply #3 on: Jul 23, 2018
You're welcome


« previous next »
 

Did you know?

Before a vaccine is licensed in the USA, the Food and Drug Administration (FDA) reviews it for safety and effectiveness. The CDC then reviews all studies again, as well as the American Academy of Pediatrics and the American Academy of Family Physicians. Every lot of vaccine is tested before administration to the public, and the FDA regularly inspects vaccine manufacturers' facilities.

Did you know?

Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.

Did you know?

The familiar sounds of your heart are made by the heart's valves as they open and close.

Did you know?

Every flu season is different, and even healthy people can get extremely sick from the flu, as well as spread it to others. The flu season can begin as early as October and last as late as May. Every person over six months of age should get an annual flu vaccine. The vaccine cannot cause you to get influenza, but in some seasons, may not be completely able to prevent you from acquiring influenza due to changes in causative viruses. The viruses in the flu shot are killed—there is no way they can give you the flu. Minor side effects include soreness, redness, or swelling where the shot was given. It is possible to develop a slight fever, and body aches, but these are simply signs that the body is responding to the vaccine and making itself ready to fight off the influenza virus should you come in contact with it.

Did you know?

Complications of influenza include: bacterial pneumonia, ear and sinus infections, dehydration, and worsening of chronic conditions such as asthma, congestive heart failure, or diabetes.

A severe food shortage occurred in the Netherlands during the “Hunger Winter” of 1944–1945. A severe food shortage occurred in the Netherlands during the “Hunger Winter” of 1944–1945.
Severe acne. Severe acne.
Alternative Splicing Alternative Splicing
Alternative Pathway Alternative Pathway
Systemic Circulation Systemic Circulation
Systemic Circulation Systemic Circulation
Video: Protein catabolism - deamination

For a complete list of videos, visit our video library