« previous next »

Author Question: Ketoconazole is used as an alternative to amphotericin B for less severe systemic mycosis. Which are ... (Read 56 times)

tingc95

  • Hero Member
  • *****
  • Posts: 556
on: Jul 23, 2018
Ketoconazole is used as an alternative to amphotericin B for less severe systemic mycosis. Which are the primary reasons for choosing ketoconazole? (Select all that apply.)
 
  a. It can be given orally.
  b. It can be used safely in patients with he-patic dysfunction.
  c. It can be given once weekly rather than daily.
  d. It is effective for severe, acute infections.
  e. It is less toxic.

Question 2

A nurse is caring for a patient who has a superficial fungal infection and notes that the provider has ordered 200 mg of ketoconazole Nizoral 200 mg PO once daily. Which action by the nurse is correct?
 
  a. Administer the drug as ordered.
  b. Contact the provider to discuss twice daily dosing.
  c. Discuss a 400-mg daily drug regimen with the provider.
  d. Request an order for a different antifungal medication.


gasdhashg

  • Sr. Member
  • ****
  • Posts: 335
Reply #1 on: Jul 23, 2018
Answer to Question 1

A, E
Ketoconazole is given instead of amphotericin B because it is less toxic and can be administered orally. Amphotericin B is administered intravenously. Ketoconazole is hepatotoxic; it is given daily. Ketoconazole is less useful for severe, acute infections.

Answer to Question 2

D
Because of the risk of serious and potentially fatal hepatic necrosis with oral ketoconazole, it is not recommended for use in treating superficial fungal infections. Another antifungal medication should be ordered.


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question

tingc95

  • Hero Member
  • *****
  • Posts: 556
Reply #2 on: Jul 23, 2018
TY


gasdhashg

  • Sr. Member
  • ****
  • Posts: 335
Reply #3 on: Jul 23, 2018
You're welcome


« previous next »
 

Did you know?

Though Candida and Aspergillus species are the most common fungal pathogens causing invasive fungal disease in the immunocompromised, infections due to previously uncommon hyaline and dematiaceous filamentous fungi are occurring more often today. Rare fungal infections, once accurately diagnosed, may require surgical debridement, immunotherapy, and newer antifungals used singly or in combination with older antifungals, on a case-by-case basis.

Did you know?

Excessive alcohol use costs the country approximately $235 billion every year.

Did you know?

The training of an anesthesiologist typically requires four years of college, 4 years of medical school, 1 year of internship, and 3 years of residency.

Did you know?

According to animal studies, the typical American diet is damaging to the liver and may result in allergies, low energy, digestive problems, and a lack of ability to detoxify harmful substances.

Did you know?

Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

Severe periodontitis in a patient with uncontrolled diabetes. Severe periodontitis in a patient with uncontrolled diabetes.
Severe arthritis can make everyday activities, like writing, typing, and handling objects Severe arthritis can make everyday activities, like writing, typing, and handling objects
Systemic Circulation Systemic Circulation
Complementation analysis of alternative outcomes of two wingless mutations Complementation analysis of alternative outcomes of two wingless mutations
Alternative pre- mRNA processing of the rat-tropomyosin gene Alternative pre- mRNA processing of the rat-tropomyosin gene
Alternative sigma factors for heat shock genes Alternative sigma factors for heat shock genes
Video: What Are Carbohydrates? Importance of Carbs & High Carb Food

For a complete list of videos, visit our video library