Answer to Question 1
B
Drugs that induce PGP can increase drug export from cells of the intestinal epithelium into the intestinal lumen, thus decreasing absorption of the drug. PGP inducers also increase drug elimi-nation and decrease brain and fetal drug exposure.
Answer to Question 2
A, D, E
Propofol can cause profound respiratory depression. It has a relatively narrow therapeutic range and can cause death from respiratory arrest. Facilities for respiratory support should be imme-diately available. Propofol infusion syndrome may occur in patients receiving prolonged, high-dose infusion, and CPK levels should be monitored and the drug should be stopped if they are >5000 u/L. Propofol can cause transient pain at the IV site, which can be minimized by in-jecting IV lidocaine at the site just before injecting. The infusion rate should never be greater than 4 mg/kg/hr. There is a high risk of bacterial infection, so opened vials need to be discarded within 6 hours.
The tone of the nurse-patient introduction sets the stage for the patient interview and patient care
A goniometer is used to measure range of motion of the patient’s arm.
Barriers that a drug administered by the oral route must cross before interacting with a target ...
Different routes of parenteral drug administration.
Graph showing oral administration of a single-dose drug. The time of onset is 2 hours and the end of ...
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