Author Question: A patient has been taking methadone Dolophine for 5 months to overcome an opioid addiction. The ... (Read 152 times)

piesebel · **on:** Jul 23, 2018

A patient has been taking methadone Dolophine for 5 months to overcome an opioid addiction. The nurse should monitor the patient for which of the following electrocardiographi c changes?

a. Prolonged QT interval
b. Prolonged P-R interval
c. AV block
d. An elevated QRS complex

Question 2

A patient received atropine intravenously before surgery. The recovery room nurse notes that the patient is delirious upon awakening and has a heart rate of 96 beats per minute,

a respiratory rate of 22 breaths per minute, and a blood pressure of 110/78 mm Hg. The nurse notifies the anesthe-siologist, who will order:
a. activated charcoal to minimize intestinal absorption of the antimuscarinic agent.
b. an acetylcholinesteras e inhibitor to com-pete with the antimuscarinic agent at re-ceptors.
c. an antipsychotic medication to treat the patient's central nervous system symp-toms.
d. ipratropium bromide Atrovent to counter the respiratory effects of the antimusca-rinic agent.

allisonblackmore · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

A
Methadone prolongs the QT interval. It does not prolong the P-R interval, cause AV block, or produce an elevated QRS complex.

Answer to Question 2

B
This patient is showing signs of antimuscarinic toxicity, caused by the atropine given during surgery. The most effective antidote is physostigmine, which inhibits acetylcholinesteras e, al-lowing acetylcholine to build up at cholinergic junctions and compete with the antimuscarinic agent for receptor binding. Activated charcoal is useful only if an antimuscarinic agent has been ingested, because it impedes absorption from the GI tract. Because this patient's psychotic symptoms are caused by an antimuscarinic agent, physostigmine should be given to treat the cause; an antipsychotic medication would only treat the symptom. Ipratropium bromide is an an-timuscarinic agent and would only compound the effects. This patient's respiratory rate is only mildly elevated.