This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What is the importance of correlating the dosage schedule with cell cycle-specific drug therapy? ... (Read 41 times)

xclash

  • Hero Member
  • *****
  • Posts: 681
on: Jul 24, 2018
What is the importance of correlating the dosage schedule with cell cycle-specific drug therapy?
 
  a. Ongoing proliferation of neoplastic tissue
  b. The known cellular kinetics of the neoplasm
  c. The hormonal requirements of the patient
  d. The body's response in strengthening the immune system

Question 2

The cell cycle-specific agent vincristine sulphate (Oncovin) acts in which phase of the cell's life cycle?
 
  a. S phase
  b. Mitotic phase
  c. Phase G1
  d. Phase G0


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

jessicaduplan

  • Sr. Member
  • ****
  • Posts: 337
Reply #1 on: Jul 24, 2018
Answer to Question 1

ANS: B
Cell cycle-specific agent scheduling should be correlated with the known cellular kinetics of the particular type of neoplasm being treated. This type of drug is schedule dependent and selectively toxic when the cell is in a specific phase of growth. The object of chemotherapy is to stop the proliferation of neoplastic tissue. Hormones are only used in specific types of cancer and are not related to cell cycle specificity. Immunomodulators are used to enhance the body's response in strengthening the immune system.

Answer to Question 2

ANS: B
Vinca alkaloids block the formation of the mitotic spindle during mitosis, thus inhibiting cell division. The S phase is the stage of active synthesis of two sets of DNA. Phase G1 is considered a presynthetic phase in which the cell prepares for DNA synthesis by manufacturing necessary enzymes. G0 is the largest variable in the cell cycle and, during this resting phase, the cell is not actively replicating.


xclash

  • Member
  • Posts: 681
Reply 2 on: Jul 24, 2018
YES! Correct, THANKS for helping me on my review

amit

  • Member
  • Posts: 364
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

Many people have small pouches in their colons that bulge outward through weak spots. Each pouch is called a diverticulum. About 10% of Americans older than age 40 years have diverticulosis, which, when the pouches become infected or inflamed, is called diverticulitis. The main cause of diverticular disease is a low-fiber diet.

Did you know?

More than 150,000 Americans killed by cardiovascular disease are younger than the age of 65 years.

Did you know?

According to the National Institute of Environmental Health Sciences, lung disease is the third leading killer in the United States, responsible for one in seven deaths. It is the leading cause of death among infants under the age of one year.

Did you know?

Asthma-like symptoms were first recorded about 3,500 years ago in Egypt. The first manuscript specifically written about asthma was in the year 1190, describing a condition characterized by sudden breathlessness. The treatments listed in this manuscript include chicken soup, herbs, and sexual abstinence.

Did you know?

In Eastern Europe and Russia, interferon is administered intranasally in varied doses for the common cold and influenza. It is claimed that this treatment can lower the risk of infection by as much as 60–70%.

Plasmids in a bacterial cell. Plasmids in a bacterial cell.
Leaf Cell Leaf Cell
Comparison of normal-shaped erythro- cytes and the abnormal sickle shape noted in patients with sick Comparison of normal-shaped erythro- cytes and the abnormal sickle shape noted in patients with sick
sperm cell sperm cell
Higher-Level Thinking Skills Used in Massage Therapy Higher-Level Thinking Skills Used in Massage Therapy
Assembly of a к light-chain gene in a B cell Assembly of a к light-chain gene in a B cell
Video: Subunits of DNA And Semi Conservative Replication

For a complete list of videos, visit our video library