This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What is the importance of correlating the dosage schedule with cell cycle-specific drug therapy? ... (Read 10 times)

xclash

  • Hero Member
  • *****
  • Posts: 681
on: Jul 24, 2018
What is the importance of correlating the dosage schedule with cell cycle-specific drug therapy?
 
  a. Ongoing proliferation of neoplastic tissue
  b. The known cellular kinetics of the neoplasm
  c. The hormonal requirements of the patient
  d. The body's response in strengthening the immune system

Question 2

The cell cycle-specific agent vincristine sulphate (Oncovin) acts in which phase of the cell's life cycle?
 
  a. S phase
  b. Mitotic phase
  c. Phase G1
  d. Phase G0


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

jessicaduplan

  • Sr. Member
  • ****
  • Posts: 337
Reply #1 on: Jul 24, 2018
Answer to Question 1

ANS: B
Cell cycle-specific agent scheduling should be correlated with the known cellular kinetics of the particular type of neoplasm being treated. This type of drug is schedule dependent and selectively toxic when the cell is in a specific phase of growth. The object of chemotherapy is to stop the proliferation of neoplastic tissue. Hormones are only used in specific types of cancer and are not related to cell cycle specificity. Immunomodulators are used to enhance the body's response in strengthening the immune system.

Answer to Question 2

ANS: B
Vinca alkaloids block the formation of the mitotic spindle during mitosis, thus inhibiting cell division. The S phase is the stage of active synthesis of two sets of DNA. Phase G1 is considered a presynthetic phase in which the cell prepares for DNA synthesis by manufacturing necessary enzymes. G0 is the largest variable in the cell cycle and, during this resting phase, the cell is not actively replicating.


xclash

  • Member
  • Posts: 681
Reply 2 on: Jul 24, 2018
Wow, this really help

matt95

  • Member
  • Posts: 317
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

Today, nearly 8 out of 10 pregnant women living with HIV (about 1.1 million), receive antiretrovirals.

Did you know?

Dogs have been used in studies to detect various cancers in human subjects. They have been trained to sniff breath samples from humans that were collected by having them breathe into special tubes. These people included 55 lung cancer patients, 31 breast cancer patients, and 83 cancer-free patients. The dogs detected 54 of the 55 lung cancer patients as having cancer, detected 28 of the 31 breast cancer patients, and gave only three false-positive results (detecting cancer in people who didn't have it).

Did you know?

Many people have small pouches in their colons that bulge outward through weak spots. Each pouch is called a diverticulum. About 10% of Americans older than age 40 years have diverticulosis, which, when the pouches become infected or inflamed, is called diverticulitis. The main cause of diverticular disease is a low-fiber diet.

Did you know?

A cataract is a clouding of the eyes' natural lens. As we age, some clouding of the lens may occur. The first sign of a cataract is usually blurry vision. Although glasses and other visual aids may at first help a person with cataracts, surgery may become inevitable. Cataract surgery is very successful in restoring vision, and it is the most frequently performed surgery in the United States.

Did you know?

Atropine, along with scopolamine and hyoscyamine, is found in the Datura stramonium plant, which gives hallucinogenic effects and is also known as locoweed.

meiotic cell division meiotic cell division
Plant Cell Plant Cell
Citric Acid Cycle Citric Acid Cycle
Plasma protein binding and drug availability: (a) drug exists in a free state or bound to plasma pro Plasma protein binding and drug availability: (a) drug exists in a free state or bound to plasma pro
Drug Classification and Description of Use Drug Classification and Description of Use
nitrogen cycle nitrogen cycle
Video: Medullary osmotic gradient: countercurrent multiplier, urea recycling & vasa recta countercurrent exchange

For a complete list of videos, visit our video library