Clients with prolonged use of which of the following ...

[mcmcdaniel]

Clients with prolonged use of which of the following anti-inflammatory drugs should be monitored for development of adverse hematological effects?
 
  a. ketoprofen c. ketorolac
  b. ibuprofen d. phenylbutazone

Question 2

The nurse understands that celecoxib (Celebrex):
 
  a. has a higher incidence of gastrointestinal bleeding than aspirin.
  b. may be useful as a platelet inhibitor.
  c. is a Cox-2 prostaglandin inhibitor.
  d. costs about the same as aspirin for therapeutic uses.

[emsimon14]

Answer to Question 1

ANS: D

Feedback
A Incorrect: Ketoprofen is not associated with hematologic adverse effects.
B Incorrect: Ibuprofen is not associated with hematologic adverse effects.
C Incorrect: Ketorolac is not associated with hematologic adverse effects.
D Correct: Prolonged use of phenylbutazone has been associated with aplastic anemia and other hematologic adverse effects.

Answer to Question 2

ANS: C

Feedback
A Incorrect: Celecoxib has a lower incidence of GI bleeding than aspirin.
B Incorrect: Although it can affect platelet aggregation, celecoxib is not used as a platelet inhibitor.
C Correct: Celecoxib is a Cox-2 inhibitor that has no= effect on the protective Cox-1 prostaglandins.
D Incorrect: Celecoxib is more expensive than aspirin because it is still under exclusive patent.

[mcmcdaniel]

Excellent

[kswal303]

TYSM