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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Each year in the United States, there are approximately six million pregnancies. This means that at any one time, about 4% of women in the United States are pregnant.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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The calories found in one piece of cherry cheesecake could light a 60-watt light bulb for 1.5 hours.