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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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Russia has the highest death rate from cardiovascular disease followed by the Ukraine, Romania, Hungary, and Poland.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Bacteria have been found alive in a lake buried one half mile under ice in Antarctica.