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The horizontal fraction bar was introduced by the Arabs.
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Interferon was scarce and expensive until 1980, when the interferon gene was inserted into bacteria using recombinant DNA technology, allowing for mass cultivation and purification from bacterial cultures.
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Certain topical medications such as clotrimazole and betamethasone are not approved for use in children younger than 12 years of age. They must be used very cautiously, as directed by a doctor, to treat any child. Children have a much greater response to topical steroid medications.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.