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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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There are 60,000 miles of blood vessels in every adult human.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.