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It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.
By definition, when a medication is administered intravenously, its bioavailability is 100%.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
Women are two-thirds more likely than men to develop irritable bowel syndrome. This may be attributable to hormonal changes related to their menstrual cycles.
Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.