Author Question: How does hemolytic disease of the fetus and newborn (HDFN) cause acquired congenital hemolytic anemia? (Read 29 times)

faduma · **on:** Aug 28, 2021

Question 1

What is the most common cause of insufficient erythropoiesis in children?

◦ Folic acid deficiency
◦ Iron deficiency
◦ Hemoglobin abnormality
◦ Erythrocyte abnormality

Question 2

How does hemolytic disease of the fetus and newborn (HDFN) cause acquired congenital hemolytic anemia?

◦ HDFN develops when hypoxia or dehydration causes the erythrocytes to change shapes, which are then recognized as foreign and removed from circulation.
◦ HDFN is an alloimmune disease in which the mother’s immune system produces antibodies against fetal erythrocytes, which are recognized as foreign and removed from circulation.
◦ HDFN develops when the polycythemia present in fetal life continues after birth, causing the excessive number of erythrocytes to be removed from circulation.
◦ HDFN is an autoimmune disease in which the fetus’s immune system produces antibodies against fetal erythrocytes, which are recognized as foreign and removed from circulation.

tdewitt · **Reply #1 on:** Aug 28, 2021

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