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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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There are 20 feet of blood vessels in each square inch of human skin.
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The shortest mature adult human of whom there is independent evidence was Gul Mohammed in India. In 1990, he was measured in New Delhi and stood 22.5 inches tall.
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It is difficult to obtain enough calcium without consuming milk or other dairy foods.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.