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Author Question: Explain how the action of E. coli O157:H7 toxin is related to the development of HUS. What will ... (Read 65 times)

bobypop

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on: Jun 25, 2018
Explain how the action of E. coli O157:H7 toxin is related to the development of HUS.
 
  What will be an ideal response?

Question 2

A patient who presents with DIC would most likely have which of the following sets of coagulation test results?
 
  PT aPTT D-dimer Fibrinogen
  a. Prolonged Prolonged Elevated Decreased
  b. Normal Prolonged Normal Normal
  c. Prolonged Prolonged Decreased Increased
  d. Normal Prolonged Decreased Decreased


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ASDFGJLO

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Reply #1 on: Jun 25, 2018
Answer to Question 1

Answer: The Shigalike toxin of E. Coli O157:H7 has an affinity for the endothelial cells of the vessels in the glomerulus. The toxin is absorbed from the intestine, the B subunits bind to Gb3 receptors on the cells, and the A subunit inhibits the protein synthesis. This results in cell death.

Answer to Question 2

Correct Answer: A


bobypop

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Reply 2 on: Jun 25, 2018
Great answer, keep it coming :)

momolu

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Reply 3 on: Yesterday
Thanks for the timely response, appreciate it

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