This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Discuss the various factors that can lead to vitamin B12 ... (Read 12 times)

bobthebuilder

  • Hero Member
  • *****
  • Posts: 567
on: Aug 20, 2018
Discuss the various factors that can lead to vitamin B12 deficiency.

Question 2

Why are folate and vitamin B12 so important to each other?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

TDubDCFL

  • Sr. Member
  • ****
  • Posts: 357
Reply #1 on: Aug 20, 2018
Answer to Question 1

It can result from inadequate intake or poor absorption. Primary B12 deficiency is sometimes seen in vegans or infants being fed by B12-deficient mothers. Secondary B12 deficiency occurs when gastric cells do not produce intrinsic factor or hydrochloric acid as a result of age, genetic defects, GI infections, surgeries, or medications.

Answer to Question 2

Folate and B12 are both required to produce methionine from homocysteine. A deficiency of either of these vitamins causes a build-up of homocysteine. High levels of homocysteine are associated with increased risk for heart disease. Folate deficiency can mask vitamin B12 deficiency. Megaloblastic, macrocytic anemia associated with primary and secondary vitamin B12 deficiency is caused by secondary folate (THF) deficiency. Folate gets trapped as inactive 5-methyl THF when vitamin B12 is not available. Severe neurological damage can occur and be fatal if B12 deficiency is misdiagnosed as a folate deficiency.


bobthebuilder

  • Member
  • Posts: 567
Reply 2 on: Aug 20, 2018
Gracias!

ttt030911

  • Member
  • Posts: 315
Reply 3 on: Yesterday
Great answer, keep it coming :)

« previous next »
 

Did you know?

People with alcoholism are at a much greater risk of malnutrition than are other people and usually exhibit low levels of most vitamins (especially folic acid). This is because alcohol often takes the place of 50% of their daily intake of calories, with little nutritional value contained in it.

Did you know?

The U.S. Pharmacopeia Medication Errors Reporting Program states that approximately 50% of all medication errors involve insulin.

Did you know?

Inotropic therapy does not have a role in the treatment of most heart failure patients. These drugs can make patients feel and function better but usually do not lengthen the predicted length of their lives.

Did you know?

Addicts to opiates often avoid treatment because they are afraid of withdrawal. Though unpleasant, with proper management, withdrawal is rarely fatal and passes relatively quickly.

Did you know?

According to the American College of Allergy, Asthma & Immunology, more than 50 million Americans have some kind of food allergy. Food allergies affect between 4 and 6% of children, and 4% of adults, according to the CDC. The most common food allergies include shellfish, peanuts, walnuts, fish, eggs, milk, and soy.

Alterable and unalterable risk factors for hypertension. Alterable and unalterable risk factors for hypertension.
Stroke Risk Factors Stroke Risk Factors
Vitamin B12 Vitamin B12
potatoes as a very good source of vitamin B6 potatoes as a very good source of vitamin B6
Factors Affecting the Affinity of Hb for O2 Factors Affecting the Affinity of Hb for O2
Oxidative stress can begin in childhood and lead to progressive damage throughout life Oxidative stress can begin in childhood and lead to progressive damage throughout life
Video: Polymerase chain reaction PCR - Animation

For a complete list of videos, visit our video library