This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: Discuss the various factors that can lead to vitamin B12 ... (Read 50 times)

bobthebuilder

  • Hero Member
  • *****
  • Posts: 567
on: Aug 20, 2018
Discuss the various factors that can lead to vitamin B12 deficiency.

Question 2

Why are folate and vitamin B12 so important to each other?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

TDubDCFL

  • Sr. Member
  • ****
  • Posts: 357
Reply #1 on: Aug 20, 2018
Answer to Question 1

It can result from inadequate intake or poor absorption. Primary B12 deficiency is sometimes seen in vegans or infants being fed by B12-deficient mothers. Secondary B12 deficiency occurs when gastric cells do not produce intrinsic factor or hydrochloric acid as a result of age, genetic defects, GI infections, surgeries, or medications.

Answer to Question 2

Folate and B12 are both required to produce methionine from homocysteine. A deficiency of either of these vitamins causes a build-up of homocysteine. High levels of homocysteine are associated with increased risk for heart disease. Folate deficiency can mask vitamin B12 deficiency. Megaloblastic, macrocytic anemia associated with primary and secondary vitamin B12 deficiency is caused by secondary folate (THF) deficiency. Folate gets trapped as inactive 5-methyl THF when vitamin B12 is not available. Severe neurological damage can occur and be fatal if B12 deficiency is misdiagnosed as a folate deficiency.


bobthebuilder

  • Member
  • Posts: 567
Reply 2 on: Aug 20, 2018
Wow, this really help

Jsherida

  • Member
  • Posts: 314
Reply 3 on: Yesterday
Excellent

« previous next »
 

Did you know?

The FDA recognizes 118 routes of administration.

Did you know?

A seasonal flu vaccine is the best way to reduce the chances you will get seasonal influenza and spread it to others.

Did you know?

Women are two-thirds more likely than men to develop irritable bowel syndrome. This may be attributable to hormonal changes related to their menstrual cycles.

Did you know?

Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).

Did you know?

Children of people with alcoholism are more inclined to drink alcohol or use hard drugs. In fact, they are 400 times more likely to use hard drugs than those who do not have a family history of alcohol addiction.

Sociologists study the social factors that underlie human behavior, the experiences that mold us, ... Sociologists study the social factors that underlie human behavior, the experiences that mold us, ...
Calcium Salts and Vitamin D Therapy Calcium Salts and Vitamin D Therapy
Structure of vitamin B12 Structure of vitamin B12
Mediator as a bridge between gene-specific regulatory factors and the general transcription Mediator as a bridge between gene-specific regulatory factors and the general transcription
Certain foods and lifestyle factors contribute to heartburn Certain foods and lifestyle factors contribute to heartburn
Hormonal and nervous factors influencing blood pressure Hormonal and nervous factors influencing blood pressure
Video: Lipid catabolism ( ketogenesis and oxidation of glycerol) and Lipid anabolism (lipogenesis)

For a complete list of videos, visit our video library