This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What is the primary function of the P450 enzymes in the liver? What will be an ideal ... (Read 57 times)

renzo156

  • Hero Member
  • *****
  • Posts: 526
on: Jun 22, 2018
What is the primary function of the P450 enzymes in the liver?
 
  What will be an ideal response?

Question 2

Mathematically, how does one determine a drug's therapeutic index?
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Jane

  • Sr. Member
  • ****
  • Posts: 309
Reply #1 on: Jun 22, 2018
Answer to Question 1

To metabolize toxic chemicals introduced into the body into less active/toxic molecules or into more water-soluble (ionized) molecules that can be excreted more rapidly from the body via the kidneys (although sometimes the metabolites produced may actually become more active or toxic than the parent compound)

Answer to Question 2

First determine the dose that produces a specified or desired effect in 50 of a sample of individuals/animals (ED50) and the dose that produces lethality in 50 of a similar sample of individuals/animals (LD50), and then divide the LD50 by the ED50.


renzo156

  • Hero Member
  • *****
  • Posts: 526
Reply #2 on: Jun 22, 2018
Thank you


Jane

  • Sr. Member
  • ****
  • Posts: 309
Reply #3 on: Jun 22, 2018
No problem :)


« previous next »
 

Did you know?

The most common childhood diseases include croup, chickenpox, ear infections, flu, pneumonia, ringworm, respiratory syncytial virus, scabies, head lice, and asthma.

Did you know?

Approximately 500,000 babies are born each year in the United States to teenage mothers.

Did you know?

According to research, pregnant women tend to eat more if carrying a baby boy. Male fetuses may secrete a chemical that stimulates their mothers to step up her energy intake.

Did you know?

Immunoglobulin injections may give short-term protection against, or reduce severity of certain diseases. They help people who have an inherited problem making their own antibodies, or those who are having certain types of cancer treatments.

Did you know?

Most women experience menopause in their 50s. However, in 1994, an Italian woman gave birth to a baby boy when she was 61 years old.

The thymus, a primary lymphoid organ where T cells mature. The thymus, a primary lymphoid organ where T cells mature.
How to write a sine function when given the amplitude, period, and phase shift How to write a sine function when given the amplitude, period, and phase shift
How to use the product rule to find the derivative of a function How to use the product rule to find the derivative of a function
Passive stretching enhances joint function. Passive stretching enhances joint function.
State the transformations on the function f(x)= 4sin(x-pi)-2 and then graph two cycles below. State the transformations on the function f(x)= 4sin(x-pi)-2 and then graph two cycles below.
Comparison of loss- and gain-of-function alleles Comparison of loss- and gain-of-function alleles
Video: Olfaction. or the sense of smell

For a complete list of videos, visit our video library