This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: What is the primary function of the P450 enzymes in the liver? What will be an ideal ... (Read 117 times)

renzo156

  • Hero Member
  • *****
  • Posts: 526
on: Jun 22, 2018
What is the primary function of the P450 enzymes in the liver?
 
  What will be an ideal response?

Question 2

Mathematically, how does one determine a drug's therapeutic index?
 
  What will be an ideal response?


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Jane

  • Sr. Member
  • ****
  • Posts: 309
Reply #1 on: Jun 22, 2018
Answer to Question 1

To metabolize toxic chemicals introduced into the body into less active/toxic molecules or into more water-soluble (ionized) molecules that can be excreted more rapidly from the body via the kidneys (although sometimes the metabolites produced may actually become more active or toxic than the parent compound)

Answer to Question 2

First determine the dose that produces a specified or desired effect in 50 of a sample of individuals/animals (ED50) and the dose that produces lethality in 50 of a similar sample of individuals/animals (LD50), and then divide the LD50 by the ED50.


renzo156

  • Hero Member
  • *****
  • Posts: 526
Reply #2 on: Jun 22, 2018
Thank you


Jane

  • Sr. Member
  • ****
  • Posts: 309
Reply #3 on: Jun 22, 2018
No problem :)


« previous next »
 

Did you know?

The average adult has about 21 square feet of skin.

Did you know?

Many supplement containers do not even contain what their labels say. There are many documented reports of products containing much less, or more, that what is listed on their labels. They may also contain undisclosed prescription drugs and even contaminants.

Did you know?

In 1886, William Bates reported on the discovery of a substance produced by the adrenal gland that turned out to be epinephrine (adrenaline). In 1904, this drug was first artificially synthesized by Friedrich Stolz.

Did you know?

Pope Sylvester II tried to introduce Arabic numbers into Europe between the years 999 and 1003, but their use did not catch on for a few more centuries, and Roman numerals continued to be the primary number system.

Did you know?

Studies show that systolic blood pressure can be significantly lowered by taking statins. In fact, the higher the patient's baseline blood pressure, the greater the effect of statins on his or her blood pressure.

Spinal cord—levels of injury; A, areas of sensory function (dermatomes); B, areas of motor function. Spinal cord—levels of injury; A, areas of sensory function (dermatomes); B, areas of motor function.
Fatty liver disease and cirrhosis of the liver. Fatty liver disease and cirrhosis of the liver.
How to use the product rule to find the derivative of a function How to use the product rule to find the derivative of a function
Oxygen affinity of hemoglobin as a function of pH Oxygen affinity of hemoglobin as a function of pH
Solve the following log function: Solve the following log function:
Differentiation of Inverse Trigonometric Function Differentiation of Inverse Trigonometric Function
Video: Energy inputs and release in glycolysis Animation

For a complete list of videos, visit our video library